Front | Back |
Name 5 predisposing factors to squamous cell carcinoma
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Tobacco and alcohol use
Chronic strictures Achalasia Diverticula Upper esophageal webs |
What is the likely diagnosis of this image, taken from the middle 1/3 of the esophagus? |
Squamous cell carcinoma
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What is the prevalence of SCCA and adenocarcinoma in the US and worldwide?
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In US they are equal, and represent about 1% of total cancer
Worldwide, SCCA accounts for 90% of esophageal cancers, and adenocarcinoma only 10% |
This image is taken from the esophagus of a patient with longstanding GERD. What is the diagnosis, and what is the lifetime risk of adenocarcinoma in patients with this condition? |
Barrett's esophagus with dysplasia 10% lifetime risk of adenocarcinoma |
This patient developed this condition after longstanding Barrett's esophagus. What is the diagnosis and what are the key histological findings? |
Adenocarcinoma, seen here in endoscopic view Malignant, intestinal type glands in the distal 1/3 of the esophagus are typical of adenocarcinoma |
Which compartment gives rise to most stomach cancers, Foveolar or Glandular?
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Glandular
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What percent of primary gastric malignancies are adenocarcinomas?
What percent of cancer deaths? Where is there highest prevalence? |
95%
2.5% Japan, Iceland |
What type of adenocarcinoma is this? |
Intestinal
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What type of adenocarcinoma is this? |
Diffuse (aka signet ring because of crescent shaped nucleus at the edge of the cell because of mucin vacuoles pushing on it)
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Where are Sister Mary Joseph nodules?
Virchow sentinel node? Krukenberg tumor? |
Periumbilical area
Supraclavicular area Ovaries |
What is the pathology seen here? |
Linitis plastica from adenocarcinoma
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What CD number is associated with GIST?
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CD-117 (c-kit)
Proliferation of interstitial cells of Cajal (pacemaker of gut) |
What are the most common sites for gastric carcinoids?
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SI (39%)
Appendix (26) Rectum (15) Bronchial system of lungs (10) Colon (5-7) Stomach (2-4) Pancreas (2-3) Liver (<1) |
What is this? |
GIST Gastrointestinal stromal tumor (gross appearance seen here) |