Neoplasms of the Esophagus and Stomach

2 Lectures on neoplasms in the the esophagus and stomach

14 cards   |   Total Attempts: 194
  

Cards In This Set

Front Back
Name 5 predisposing factors to squamous cell carcinoma
Tobacco and alcohol use
Chronic strictures
Achalasia
Diverticula
Upper esophageal webs
Question 2
What is the likely diagnosis of this image, taken from the middle 1/3 of the esophagus?
Squamous cell carcinoma
What is the prevalence of SCCA and adenocarcinoma in the US and worldwide?
In US they are equal, and represent about 1% of total cancer
Worldwide, SCCA accounts for 90% of esophageal cancers, and adenocarcinoma only 10%
Question 4
This image is taken from the esophagus of a patient with longstanding GERD. What is the diagnosis, and what is the lifetime risk of adenocarcinoma in patients with this condition?
Answer 4
Barrett's esophagus with dysplasia
10% lifetime risk of adenocarcinoma
Question 5
This patient developed this condition after longstanding Barrett's esophagus. What is the diagnosis and what are the key histological findings?
Answer 5
Adenocarcinoma, seen here in endoscopic view
Malignant, intestinal type glands in the distal 1/3 of the esophagus are typical of adenocarcinoma
Which compartment gives rise to most stomach cancers, Foveolar or Glandular?
Glandular
What percent of primary gastric malignancies are adenocarcinomas?
What percent of cancer deaths?
Where is there highest prevalence?
95%
2.5%
Japan, Iceland
Question 8
What type of adenocarcinoma is this?
Intestinal
Question 9
What type of adenocarcinoma is this?
Diffuse (aka signet ring because of crescent shaped nucleus at the edge of the cell because of mucin vacuoles pushing on it)
Where are Sister Mary Joseph nodules?
Virchow sentinel node?
Krukenberg tumor?
Periumbilical area
Supraclavicular area
Ovaries
Question 11
What is the pathology seen here?
Linitis plastica from adenocarcinoma
What CD number is associated with GIST?
CD-117 (c-kit)
Proliferation of interstitial cells of Cajal (pacemaker of gut)
What are the most common sites for gastric carcinoids?
SI (39%)
Appendix (26)
Rectum (15)
Bronchial system of lungs (10)
Colon (5-7)
Stomach (2-4)
Pancreas (2-3)
Liver (<1)
Question 14
What is this?
Answer 14
GIST
Gastrointestinal stromal tumor (gross appearance seen here)