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Related Flashcards
Cards In This Set
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FIRST-PASS
EFFECT
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* All drugs which are
absorbed after ORAL administration pass directly to the HEPATIC-PORTAL CIRCULATION, which carries blood to the liver before it is distributed to other body tissues. Therefore some drugs may be INACTIVATED before they reach the SYSTEMIC CIRCULATION
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MINIMUM
EFFECTIVE CONCENTRATION:
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The minimum amount of concentration to produce a theraputic effecte
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Toxic Concentration
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The amount of medication to produce a toxic effect
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Theraputic range
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The blood plasma concentration between to minimum effective concentration and toxic concentration
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Plasma half life
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The length of time needed for the concentration of drug to decrease by half
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Goal of drug therapy
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Produce doses to a desired effect without any adverse side effects
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Therapeutic index
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Relationship between and a drugs median effective dose to its median lethal dose
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Efficacy
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The magnitude of the maximum response produced by the drug
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5 rights to drug administration
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PMDRTD
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NURSING PROCESS
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ADPIE
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Drug classes
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Pharmacologicaltherapuetic chemical
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