+
Related Flashcards
Related Topics
Cards In This Set
| Front | Back |
|
State the three most important characteristics of any drug.
|
Effectiveness, safety, and selectivity
|
|
Is it possible to have a selective drug?
|
No, all drugs can cause side effects
|
|
Define pharmacokinetics:
|
How much of the drug gets to the site of action via Absorption, distribution, metabolism, and excretion.
|
|
Define pharmacodynamics.
|
Determines nature and intensity of the response after binding to receptors
|
|
Who is the most likely member of the health care team to observe and evaluate drug responses and to intervene if required?
|
The nurse
|
|
What are the three basic goals of pre administration assessment of medications
|
Collecting baseline data (therapeutic and adverse responses), identify high-risk patients, assessing capacity for self-care.
|
|
State the factors that can predispose an individual to adverse reactions from drugs
|
Pathophysiology (liver and kidney dysfunction), genetics, allergies, pregnancy, age (very young/old).
|
|
What are measures to reduce adverse effects of medication administration?
|
Identify high-risk patients, ensure proper administration, educate patients that might precipitate an adverse reaction.
|
|
Which Amendment strengthened drug regulation after the thalidomide tragedy in Europe?
|
The Harris-Kefauver Amendments in response to a sedative that caused the birth defect phocomelia).
|
|
What type of research is required to assess drug therapies?
|
Randomized controlled trials
|
|
What is a “blinded” study?
|
People involved do not know to which group subjects have been randomized. Single: subjects blinded Double: researchers and subjects are blinded
|
|
What is the purpose of having a trade name for a drug?
|
Easy recall and pronunciation
|
|
What is the problem with trade names?
|
Clouds communication of the drug and promotes medication errors.
|
|
What are the limitations of the testing procedures used to bring drugs to market?
|
Testing is limited on women of childbearing age and children and the failure to detect all adverse effects.
|
|
How much does it cost to develop a new drug in the US?
|
$800 million
|
