Pathology Chapter 2

Acute inflammation. See neutrophils (trilobed)

Early (neutrophilic) (left) and later (mononuclear) cellular infiltrates (right) of infarcted myocardium

Margination & diapedesis of neutrophils

Exudation
Vasodilation with exudation has led to an outpouring of fluid with fibrin into alveolar spaces, along with PMN's.

Exudation of fibrin
Fibrin mesh in fluid with PMN's in acute inflammation that produces "tumor" or swelling of acute inflammation

Serous inflammation
•Thin, watery exudate with insufficient amounts of fibrinogen to form fibrin material. eg. blister fluid

•Fibrinogen-rich exudate that forms excess fibrin •“Bread and butter” appearance on serosal surfaces •eg. fibrinous pericarditis

•Localized collection of pus (liquefactive necrosis) with formation of an abscess •eg. Lung abscess –Liquefactive necrosis seen - purulent contents drain out leaving a cavity. Chest X-ray – Liquefied central contents appear as an "air-fluid level".

Toxin induced superficial mucosal damage. Formation of a nectrotic membrane along a mucosal surface. Pseudomembranous inflammation. Pseudomembrane colitis, pseudomembrane of diptheria

Acute bronchopneumonia.
PMNs form an exudate in the alveoli

Acute cholecystitis.
Neutrophils infiltrating mucosa and submuscosa of the gallbladder.

Granulomatous inflammation. Seen in TB and sarcoidosis.

Foreign body granuloma

Alveoli, cells with neutrophils. Broncopneumonia- exudative inflammation

Granulomatous inflammation