Patho Chapter 2

First patho e xam chap

35 cards   |   Total Attempts: 188
  

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Genes
The basic unit of inheritance
Deoxyribonucleic acid
The primary component of chromatin
Mutation
Any inherited alteration of genetic material
Base pair substitution
One base pair replacess anotherand still codes for DNA
Frameshift mutation
Insertion or deletion of one or more base pairs
Spontaneous mutations
Occurs in absence of exposure to mutagens, usually on mulational hot spots
Mutagens
Agents that increase the frequency EX radiation
Transcription
RNS is synthesized from DNA to mRNA
Translation
RNA to tRNA
Gametes
Spermand eff cells - haploid 23 chromosome
Somatic cells
All other cells veside gametes - diploid 46 chromosomes
Autosome
The first 22 of the 23 chromosomes in males and femailes
Sex chromosome
The remaining pair of X or Y
Disjunction
Normal separation of chromosomes during cell division
Nondisjunction
Usually the cause of aneuploidy