Nutrition Biochemical Assessment

Biochemical Assessment chapter

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Biochemical Tests are useful because:
Objective and quatifiable

detects deficits before anthropometric measurements are affected

defects some abnormalities before signs and symptoms appear
Uses for lab tests:
Screening for malnutrition

evaluating nutritional status

diagnosis specific nutrient deficiencies

monitor specific nutrient deficiencies

estimate risk of morbidity nad/or mortality
Static Lab Test
Measures actual level of nutrient in specimen
Weakness of Static Test:
Fails ro reflect body's overall status
Functional(indirect) Lab Test
Measures a biochemical or physiological activity that depends on the nutrient of interest
Weakness of Functional Tests:
Tendency to be non-specific, not always specific ofor nutrient of interest
Specimen Types:
Serum

Plasma

Blood Cells

Tissues

Urine

Feces
Lab Tests are chose based on:
Precision

Accuracy

sensitiviy

Specificity
Considerations when interpretating lab values:
Normal values may have different values for men, women and children

It is the average plus/minus one standard deviation

Altered by blood volume and hydration status

Diseases influence values
Serial Lab data
Is preferred
Protein Status and Biochemical Markers
Evaluate somatic and visceral protein
Somatic Protein is found:
In skeletal muscle
Viseral Protein is found:
Visceral protein found ithin organs
PEM
Protein Energy Malnutriion: usually result of disease in the US

Common in 3rd world countries

Can result in Kwashiorkor or marasmus
PEM and hospitalized patients
50% may have PEM