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What is psychosis?
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Involves loss of contact with reality
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Major side effect of using Anti psychotics?
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Parkinsons like effects, exhibit tremors and muscular rigidity, involvement with dopamine
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Give two examples of anxiety disorder
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Panic disorder
specific phobia
social phobia
OCD
PTSD
Generalized anxiety disorder
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Is schizophrenia a functional or an organic psychosis
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Functional
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Besides sadness, what are some other indicators of major depressive episode
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Diminished interest or pleasure in most activities
changes in body wieght or appetite
insomia or hyperinsomnia
fatigue/loss of energy
feelingness of worthlessness
diminished ability to think or concentrate
thoughts of death and suicide
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What type of drug is is chlropromazine and where was it first tested on patients
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First tested in France on surgical patients, it is a phenothiazine
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What is tardive dyskinesia and how does it repond to a reduction in the dose of an antipsychotic drug
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Rhythmic, repetitive sucking and smacking movements of the lips; thrusting of the tongue in and out, movements of the arms, toes or fingers, reversal is possible by lowering dose immediately
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Which type of drug was discovered while testing an antituberculosis agents?
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MAO
monoamine oxidase inhibitors
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How do the ssris differ from the older tricylics in terms of their actions in the brain
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Reuptake inhibitors for serotonin and norepinephrine, but are more slective, have fewer other actions than the tricyclics
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What were the reasons it took so long for lithium to be avalabe for use in the US
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1. salt substitute poisonings
2. mania was not seen as a major problem in the US
3. hard for research companies to recupe their research cost
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If clozapine is so dangerous, why is it prescribed at all?
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Lowers white blood count, but it produced much less pseudoparkinsonism than the other drugs, some patients who had failed to improe witht eh toher antipsychotics showed improvement
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Why was prozac the most widely prescibed antidepressant drug ever marketed?
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Safer than the other tricyclics, less likely to lead to overdose deaths
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