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Lesion
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An area of pathologically altered tissue; the two types are primary and secondary
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Primary lesions
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Lesions arising from previously normal skin
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Macule or macula (primary)
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A flat, discolored spot on the skin up to 1 cm across (e.g., a freckle)
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Patch (primary)
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A flat, discolored area on the skin larger than 1 cm (e.g., vitiligo)
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Papule (primary)
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A solid mass on the skin up to 0.5 cm in diameter (e.g., a nevus [mole])
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Plaque (primary)
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A solid mass greater than 1 cm in diameter and limited to the surface of the skin
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Nodule (primary)
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A solid mass greater than 1 cm that extends deeper into the epidermis
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Tumor (primary)
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A solid mass larger than 1-2 cm
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Wheal (primary)
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An area of localized skin edema
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Vesicle (primary)
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Little bladder; an elevated, fluid-filled sac (blister) within or under the epidermis up to 0.5 cm in diameter (e.g., a fever blister)
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Bulla (primary)
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A blister larger than 0.5 cm (e.g., a second-degree burn) (meaning = bubble)
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Pustule (primary)
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A pus-filled sac (e.g., a pimple)
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Secondary lesions
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Lesions that result in changes in primary lesions
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Erosion (secondary)
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Gnawed away; loss of superficial epidermis, leaving an area of moisture but no bleeding (e.g., area of moisture after rupture of a vesicle)
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Ulcer (secondary)
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An open sore on the skin or mucous membrane that can bleed and scar; sometimes accompanied by infection
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