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Cards In This Set
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What stage is G0?
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It is the quit stage where the cell is not in the cell cycle. Here the cells are not dividing or prepareing for division.
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_____ Phase is the stage where cells divide. It lasts ____ hours. It is the ______ (longest/shortest) phase.
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M Phase 2 hours shortest
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_____ phase is the stage where cells grow everything except for DNA. It is the ______ (longest/shortest) phase. It lasts ____ hours.
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G1 phase longest 12 hours (in a 24 hour cycle)
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____ phase is when DNA replication occurs. This lasts _____ hours.
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S phase. 5-6 hours
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_____ phase is when the cells prepares for division. It lasts ____ hours.
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G2 3-4 hours
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The cell cycle is regulated by going thru a series of _______. THey insure that damaged cells do not ______.
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Check points. replicate
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Critical regualtors of the cell cycle are proteins called _____. They act in concert with ______. ______ binding leads to activation of _______.
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Cyclins cyclin-dependent kinases (cdk's) cyclin, cdk's
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Cdk's are active only in the presence of ______.
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Cyclins
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You can know what is going on in the cell cycle just by looking at which ______ are present.
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Cyclins
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_______ stimulates the production of cyclin D.
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Mitogens
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Passage thru the G1 checkpoint requires the activation of the Transcription Factor _____.
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EF2
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______ regulates the cell cycle. Genes that are involved in the cell cycle are turned on by this TF.
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EF2
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EF2 is inactive when _____ is bound to it.
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RB
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________ of RB leads to activation of EF2. _____ phosphorylates RB.
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Phosphorylation cdk4
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EF2 stimulates the synthesis of ______ that are required for DNA synthesis and for further regualtion of steps in the cell cycle.
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Proteins
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