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What is the meaning of absorption? |
The uptake of the drug into or across body tissues or cells.
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What is the meaning of distribution of a drug? |
The movement of the drugs to the intended target tissues.
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What two factors can affect the distribution of a drug? |
Blood perfusion of the target tissue and the characteristics of the drug itself.
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What is agonism? |
A reaction.
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What is antagonism? |
To prevent.
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What is the meaning of biotransformation? |
Modification of a drug by living organisms.
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How are drugs excreted from the body? |
Unchanged or modified.
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Where are most drugs modified? |
In the liver.
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Through what two organs are most drugs excreted? |
Through the kidneys or the digestive tract.
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What can biotransformation lead to? |
Inactive drug metabolites or, in some situations, to drug metabolites that have specific effects on the body.
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What is the meaning of pharmacodynamics?
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The resulting action of drugs on living beings.
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What is the meaning of pharmacokinetics?
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The motion of drugs in a body.
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What does the motion or movement of drugs include?
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Absorption, distribution, metabolism and excretion. ADME
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How is the intended activity or response of a drug called?
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The drug's efficacy.
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What is the term used to refer to the amount of drug needed to impact target tissues and safely create the desired drug action?
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Therapeutic range.
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