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Bowman's Capsule |
Is a capsule-shaped membranous structure surrounding the glomerulus of each nephron in the kidneys of mammals that extracts wastes, excess salts, and water from the blood
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Glomerular Filtrate
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Is a renal process whereby fluid in the blood is filtered across the capillaries of the glomerulus and into the urinary space of Bowman's capsule.
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Podocytes |
Are cells in the Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus.
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Pedicels |
Is a secondary process of a podocyte, which helps form the visceral capsule of a renal corpuscle.
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Filtration Slits |
Are intercellular clefts between the interdigitatingpedicels of podocytes; they are part of the filtration barrier of renal corpuscles.
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Slit Diaphragm |
Is made of nephrin and various proteins that are synthesized by the podocytes, extends across the filtration slits.
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Nephrin
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Is a zipper-like protein that forms the slit diaphragm, with spaces between the teeth of the zipper, big enough to allow sugar and water through, but too small to allow proteins through.
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Fenestrated Endothelium
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That there are pores (fenestrae or fenestrations "windows") that penetrate through the endothelial cells.
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Glomerular-Capsular Membrane |
Is a cup-like sac at the beginning of the tubular component of a nephron in the mammalian kidney that performs the first step in the filtration of blood to form urine
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Juxtaglomerular Apparatus |
Is found next to the glomerulus. It is found between where blood enters a renal corpuscle and distal convoluted tubule of the same nephron.
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Juxtaglomerular Apparatus (function)
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This location is critical to its function in regulating renal blood flow and glomerular filtration rate.
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Macula densa |
Is an area of closely packed specialized cells lining the wall of the cortical thick ascending limb of the loop of Henle. And to the distal convoluted tubule.
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Juxtaglomerular Cells |
Are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells mainly in the walls of the afferent arterioles.
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Extraglomerular Mesangial Cells
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Are strategically positioned between the macula densa and the afferent arteriole. These cells form a syncytium.
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Syncytium |
Is a multinucleate mass of cytoplasm resulting from fusion of cells
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