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Des the morphology of Trichomonas vaginalis
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Larger than tri. Tenax
Short undulating memb.
More granules along costa and axostyle
Arranged hydrogenosomes distinguishes T. viag from other Tri Spp.
Produces pseudopodia
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Where does Trichomonas vaginalis live
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Lives in vagina & urethra of women & prostrate seminal vesicles & urethra of men
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What is the mode of tranmission of Trichomonas vaginalis
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Trans by sex
In some cases via semen in artificial insemination
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What is the required diagnosis of Trichomonas vaginalis
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Recog of trichonomad in secretion from an invitro culture made from vaginal irrigation
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What drug is used to treat Trichomonas vaginalis
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oral drug metronidazole
Sexual partners treated simultaneously to avoid reinfection
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What are the symptoms of Trichomonas vaginalis
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Some strains cause intense inflammation with itching & white discharge (leukorrhea)
In men symp are, may have irritating urethritis or prostratitis
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How does Trichomonas vaginalis multiply
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Divide by longitudinal fission
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Des the metabolism of Trichomonas vaginalis
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Trichomo aerotolerant anaerobes degrading carbohydrates incompletely to short chain organic acids & carbon dioxide.
use hydrgenosomes in place of mitochondria to produce energy
Produce molecular hydrogen in absences of oxygen
Pyruvate is produced in cytoplasm by glycolysis
Oxidation of pyruvate to acetate is coupled to substrate- level generation of ATP; thus hydrgenosome participate in energy production in cell
Metronidazole is reduced by ferrodoxin to form toxic products thus explains how drug works
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Is Trichomonas vaginalis asymptomatic
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Yes
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What 2 things make T. vaginalis differnt from Guiardia
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Produce molecular hydrogen in absences of oxygen
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What does T. vaginalis use inplace of a mitochondria
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Hydrgenosome
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