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Cell Potency
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potency specifies the potential to differentiate into different cell types
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Totipotency
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Zygote (1 day old), morula (3 days old): cells can differentiate and produce all the cells in an organism, including extraembryonic tissues
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Pluripotency
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Inner cell mass of blastocysts (5-7 days old): cells can differentiate into any of three cell masses (endoderm, mesoderm, or ectoderm); originate as inner mass cells within the blastocyst and go on to develop the spectrum of body cells and tissues
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Multipotency
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Cells from a single germ layer (ex: mesoderm) in 3 week old embryo; cells whcih can differentiate into 2 or more cell types
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Unipotency
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Terminally differentiated to form only on cell type (ex: neuron)
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Stem Cells in tissues
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Many tissues in both children and adults contain populations of stem cells that renew themselves continually and divide to produce new tissue cells as needed
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Embryology
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Study of origin and devleopment of a single individual
Prenatal period -embryonic period: first 8 weeks -fetal period: 9 weeks |
Embryonic period
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Fertilization ->1 week conceptus-> 3 week embryo (3mm) -> 5 week embryo(10mm)->8week embryo (22mm)
duration: 1st 8 weeks postfertilization major events: organs form from 3 primary germ layers; basic body plan emerges |
Embryonic disc with ectoderm, mesoderm, and endoderm
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Week 3: Three layered embryo with three types of germ cells
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Ectoderm, nervous tissue
mesoderm, muscle and connective tissue endoderm |
Ectoderm germ layer
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Brain, spinal cord, skin epidermis
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Mesoderm germ layer
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Bones, muscle, connective tissue including dermis, epithelium inside blood vessels (endothelium), epithelium linging ventral body cavities (mesothelium)
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Endodermaal germ layer
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Forms inner epithelial lining of the gut tube and its derivative respiratory tubes, digestive organs, and urinary bladder) nd secretory cells of some glands
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Major Derivatives of Embryonic Germ Layers
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4 basic tissue types & basic functions
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-Epithelial tissue: covering
-Connective tissue: support -Mucle tissue: movement -Nervous tissue: control |