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Found in humpid Africa, S America and SE Asia. Trasmitted by skin contact. Primary lesions: papules Secondary leasion: similar Tertiary late phase: cutaneous plaque, cunatous lesions with hyperkeratosis of palms and soles Name Disese |
Spirochaetaceae treponema pallidum pertenue: Yaws
Pertenue Yaws will pigment (hyperkeratosis) your paws (palms and soles) |
Found in Mexico, Central America and Colombia. Transmitted by skin contact. Primary lesion: small pruitic, red rash on face,neck,chest- can last years Secondary: scaley papules-> pigments lesions Late phase: depigments lesions on wrist, elbows, ankles Name Disese |
Spirochaetaceae treponema carateum: Pinta
Depigmented people on the Pinta to America. |
Found in Africa and West Asia. Transmission: sharing eating drinking utensils Primary: oral mucosal lesion (reaelt seen) Secondary: Mucous patches, periostitis, adenopathy Tertiary: gummatous lesions Name Disese |
Spirochaetaceae treponema pallidum Endemicum: Bejel
No Forks in Asia, b/c it end be(jel) oral gum(matous) lesoins |
Found in East Africa, S America and catastrophes Symptoms: Causes reccurent fever, chills, Headache, myalgia, arthralgia, and truncal rash. COD: myocarditis, CNS hemorrhage. Micro: organism only in blood during febrile episodes, reemerge from organs with antigenic variation with next fever Name Disease and Vectors |
Disease: Borrelia recurrentis- relapsing fever
Vector: body louse crushed and organismas go into skin- single relapse or tick borne: worldwideand rodent resvoir Stain: dark-feild, Giemsa, Wright, thin/thick smear DURING FEVER |
Epi: NE, West Coast of US, Europe during summer Stage 1:Erthema chronicum migrans w or w/o annular scondary lesions Stage 2: disseminated disease: myalgia, migratory joint pain, some meningeal irritation normal CSF, 5% have transitory cardiac problems Stage 3: latent period, then years of persistent infection- LATE ONLY abnormal CSF meningitis, bell palsy, chonic arthrutus Name disease, diagnosis and Vectors |
Disease: Borrelia burgdorferia- lyme disease
Vector: Ixodes tick scapularis: NE, pacidicus: west, ricinius: europe Resvoir: deer and rodents Diagnosis: serology is diffucult Early: 30-40% IgM 2-4 weeks: 70% IgM 4-6 weeka: 90% IgG use C6 Ab ELISA |
Epi: Worldwide Transmission: zoonosis of animal urine in water or soil Stage 1: flu-like fever, headache, muscle pain, conjunctivis (auqeous homor of eye) Stage 2: immune mediated renal liver damage, meningitis, chronic uveitis, renal failure, rash DIsease name and two forms |
Leprtospira interrogans: leptopirosis
Anicteric Form: 90% pt with flu like symptoms 4-7 days +/- secondary disease Icteric Form (Weil's Disease): renal impaments, hepatic failure, conjunctival hemorrhage, shock, 5-10% death Diagnsosis: serologic tests: ELISA, fourfold rise in antibody titer Some Humor, it lept from the urine water to you aqueous humor |