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Related Flashcards
Cards In This Set
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The concepts of solubility is important to a pharmacist because: (2)
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1.) Solubility governs the preparation of solutions as a dosage form2.) A drug must be in solution before it can be absorbed by the body
to exert biological activity |
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In order to prepare a solution, a chemical substance must be
_____ in a solvent |
Soluble
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________ is defined as the quantity of a particular substance (solute) that can dissolve in a particular solvent
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Solubility of a substance at a given temperature
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Term that is used to refer to the solute when it is a liquid and
will form a solution with a solvent over any concentration range |
Miscibility
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T or FSolubility yields a saturated solution
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True
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What is the difference btw solubility and miscibility?
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Solubility: when the solute is a solid mixes with waterMiscibility: 2 liquid solution mixing together
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Solubility as a number is the concentration of the dissolved solute when it is _______ with the undissolved solute
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In in equilibrium
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T or FAt saturated solution, the molecules are not in equilibrium
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False
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In a ________ containing undissolved solid solute, the rate at which the molecules or ions leave the solid solute surface is equal to the rate at which the dissolved molecules return to the solid and the system
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Saturated solution
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This solution contains the dissolved solute in a concentration lower than that of a saturated solution
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Unsaturated solution
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This solution contains a higher concentration of the dissolved solute than that at the dissolution equilibrium under the same conditions
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Supersaturated solution
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Most pharmaceutical solutions are considered __________
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Unsaturated
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Miligrams equivalent weights )equivalent weight expressed in mg, mEq) of solute/liter of solution
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MIlliequivalents per liter
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Osmoles of solute/liter of solution
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Osmolarity
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Osmoles of solute/1000g of solvent
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Osmolality
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