Front | Back |
Action Potential:
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Depolarization triggers an action potential which is an electrical impulse.
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What causes an action potential?
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Neuron is normally negatively charged, with enough stimulation, sodium channels open up and allow positively charged ions to enter and create depolarization.
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What happens after action potential?
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After sodium channels close and potassium channels open to release positively charged potassium ion and repolzarize back to negative state.
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Acetylcholine/ACh: location in CNS, related disease
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In peripheral and CNS.
Breakdown of ACh related to Alzhemers etc.
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Ach function
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In peripheral causes muscles to contract. In CNS involved in REM sleep, sleep wake cycle, memory.
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Dopamine: effects on, disease related to
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Personality, mood, sleep.
Schizophrenia hypothesis of high levels or overactive receptors.
Movement: oversensitivity related to Tourettes and Parkinson’s. Mood: reinforce drug use. Cocaine increase dopamine.
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Serotonin:
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Inhibitory effect.
Mood, hunger, aggression, migraine.
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Elevated seratonin leads to:
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Elevated leads to schizophrenia, autism, restriction/Anorexia.
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Low levels of seratonin lead to:
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Low levels lead to aggression, depression, suicide, Bulimia, PTSD, OCD.
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GABA: type of effect, related to what
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Inhibitory effect. Eating, seizure, anxiety, motor, vision. Benzos and CNS depressants reduce effects of GABA.
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Low GABA leads related to what diseases/conditions
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Low GABA anxiety.
Low GABA in Huntington’s disease.
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Spinal cord:
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Bundles or myelinated axons, dendrites and somas.
Info between brain and body, coordinate left/right body and controls simple reflexes
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Function of nerves in superior portion of spinal cord:
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Nerves in superior portion carry afferent/sensory messages.
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Function of nerves in inferior portion of spinal cord:
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Nerves in inferior portion transmit efferent/motor messages.
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Quadriplegia:
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Damage at cervical level.
Loss of sensory and voluntary motor function of arms and legs.
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