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Methods of movement through the plasma membrane
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Diffusion, osmosis, mediated transport, and endocytosis/exocytosis
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Types of mediated transport
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Facilitated diffusion, secondary active transport, and active transport
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Most transport will occur by ___ or ___.
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Diffusion or osmosis
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Movement of solutes from an area of higher concentration to lower concentration in solution
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Diffusion
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Difference between the concentration of two points
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Concentration gradient or density gradient
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The plasma membrane is ___, meaning it allows only certain kinds of molecules to pass
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Selectively permeable
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Non-carrier mediated transport occurs by ___
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Diffusion
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Carrier-mediated transport involves ___
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Specific protein transporters
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___ dictates how much energy the molecule will have
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Temperature
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Factors affecting membrane permeability and diffusion
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Molecule temperature, size of diffusing substance, lipid solubility of diffusing substance (partition coefficient), and membrane thickness, viscosity, and number of channel proteins
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Molecules can move through the lipid bilayer, especially if they are ___. Therefore, the rate of transport is proportional to the ___ of the molecule.
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Lipid soluble; hydrophobicity
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The rate of transport is measured by ___; the greater it is, the faster the molecule will diffuse across the membrane
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Partition coefficient
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Measure of hydrophobicity/lipophilicity; measure of the relative affinity of the molecule for lipid versus water
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Partition coefficient
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Water partition coefficient; the higher the value, the more lipophilic the substance
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Octanol
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The measure of the resistance of a fluid to deform under shear stress; it is commonly perceived as "thickness" or resistance to pouring
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Viscosity
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