Pharmacology Chapter 2

Drug interactions in which the effect of a combination of two or more drugs with similar actions is equivalent to the sum of the individual effects of the same drugs given alone. For example, 1+1=2 (compare with synergistic effects).

Any undesirable occurrence related to administering or failing to administer a prescribed medication.

Any unexpected, unintended, undesired or excessive response to a medication given at therapeutic dosages.

A general term for an undesirable effects that are a direct response to one or more drugs

A drug that binds to and stimulates the activity of one or more receptors in the body

An immunologic hypersensitivity reaction resulting from the unusual sensitivity of a patient to a particular medication; a type of adverse drug event

A drug that binds to and inhibits the activity of one or more receptors in the body. also called inhibitors.

Drug interactions in which the effect of a combination of two or more drugs is less than the sum of the individual effects of the same drugs given alone. It is usually caused by an antagonizing effect of one drug on another.

A measre of the extent of drug absortption for a given drug and route

One or more biochemical reactions involving a parent drug. Occurs mainly in the liver and produces a meabolite that is either inactive or active

The barrier system that restricts the passage of various chemicals and microscopic entities between the bloodstrean and the central nervous system. It still allows for the passage of essential sumstances such as oxygen.

The name that describes the chemical composition and molecular structure of a drug

Any condition, especially one related to a disease sate or other patient chracteristic, including current or recent drug therapy, that renders a particular form of treatment improper or undesireable.

The general name for a large class of enzymes that play a significant role in drug metabolism

A state in which there is a compulsive or chronic need, as for a drug