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Cards In This Set
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Abciximab (ReoPro) Mechanism of Action
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Prevent the aggregation of platelets by inhibiting the integrin GP Ilb/Illa receptor
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Abciximab (ReoPro) Indications
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UA/NSTEMI patients undergoing planned or emergent PCl
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Abciximab (ReoPro) Adverse Reactions
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Bleeding from the GI tract
Internal bleeding Intracranial hemorrhage Hypotension Stroke Anaphylactic shock |
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Abciximab (ReoPro) Contraindications
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Bleeding from any source
Severe uncontrolled hypertension Surgery of trauma within the previous 6 weeks Stroke within the previous 30 days Renal failure Thrombocytopenia Intracranial mass |
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Abciximab (ReoPro) Dosage
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UA/NSTEMI with Planned PCl within 24 hrs:
0.25 mg/kg IV, IO (10 to 60 mins prior to procedure), then 0.125 mcg/kg/min IV, IO infusion for 12 to 24 hrs Percutaneous Coronary Intervention Only: 0.25 mg/kg IV, IO, then 10 mcg/min IV, IO infusion |
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Activated Charcoal Mechanism of Action
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When certain chemicals and toxins are in proximity to the activated charcoal, the chemical will attach to the surface of the charcoal and become trapped.
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Activated Charcoal Indications
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Toxic ingestion
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Activated Charcoal Adverse Reactions
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Nausea/vomiting
Constipation or diarrhea If aspirated into the lungs, charcoal can induce a potentially fatal form of pneumonitis |
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Activated Charcoal Contraindications
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Ingestion of acids
Alkalis Ethanol Methanol Cyanide Ferrous sulfate or other iron salts Lithium Coma GI obstruction |
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Activated Charcoal Dosage
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Adult: 50 to 100 g/dose
Pediatric: 1 to 2 g/kg |
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Adenosine (Adenocard) Mechanism of Action
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Slows the conduction of electrical impulses at the AV node
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Adenosine (Adenocard) Indications
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Stable reentry SVT
Does not convert AF, atrial flutter, or VT |
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Adenosine (Adenocard) Adverse Reactions
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Most are mild and short-lived
Sense of impending doom Complaints of flushing Chest pressure Throat tightness Numbness May be a brief episode of asystole after administration |
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Adenosine (Adenocard) Contraindications
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Sick sinus syndrome
Second- or third degree heart block Poison- or drug-induced tachycardia |
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Adenosine (Adenocard) Dosage
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Adenosine should only be delivered by rapid IV bolus with a peripheral IV or directly into a vein, in a location s close to the heart as possible, perferably in the antecubital fossa. Administration of adenosine sould be immediately follwed by a saline flush, and then the extremity should be elevated
Adult: 6 mg rapid IV, IO (over a 1- to 3- second period) immediately followed by a 20-mL rapid saline flush If the first dogse does not eliminate the rhythm in 1 to 2 min, 12 mg IV, IO; repeat a second time if required Pediatric: For children >50kg: same as adult dosing For children <50kg: 0.1 mg/kg IV, IO (max dose; 6 mg) immediately followed by a >5-mL rapid saline flush; may repeat at 0.2 mg/kg (max dose; 12 mg) |
