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Generalized anxiety disorder
characteristics |
Uncontrolled worrying that last 6 months or long er
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Generalized anxiety disorder
treatment (nondrug) |
Supportive therapy
cognitive behavioral therapy biofeedback relaxation training |
Generalized anxiety disorder
drug therapy |
Benzodiazapines (first drug choice)
-alprazolam -lorazepam buspirone (BuSpar) |
Buspirore (BuSpar)
|
Generalized anxiert disorder medicaiton
non CNS depresant does not cause sedation has no abuse potential does not intensify the effects of CNS depressants major disadvantage - ANIOLYTIC EFFECTS develop slowly pharmocokinetics - well absorbed followng oral administration |
Buspirone (BuSpar)
adverse effects |
Dizziness
nausea headache nervousness lightheadedness excitement |
Buspirone (BuSpar)
drug and food interactions |
Erythromycin and ketoconazole
greape fruit juice |
Buspirone (BuSpar)
tolerance, dependence and abuse |
No withdrawal symptoms have been observed
|
Buspirone (BuSpar)
preparations, dosage, administration |
Tablets - intial dosage is 5,h 3x/day
may increase yp with a maximum of 60mg/day |
Antidepressants
- only these are approved for GAD |
Venlafaxine (effexor XR)
duloxetine (cymbalta) paroxetine (paxil) ---short and long term escitalopram (lexapro) |
Characteristics of Panic disorder
|
Palpitations, pounding heart, racing heartbeat
chest pain or discomfort senstaiton of shortness of breath feeling of choking dizziness, lightheadedness nausea or abdominal discomfort derealization or deprersonalizaiton fear of losing control fear of dying tingling or numbness in the hands flush or chills can lead to AGORAPHOBIA |
Panic disorder
treatment (antidepressants) |
Selective serotonin reuptake inhibitors
trycyclic antidepressants monoamne oxidase inhibitors |
Panic disorer
treatment (benzodiazepine) |
Second like drugs for panic disorder due to risk of abuse and dependence
|
Panic disorder
treatment |
Cognitive behavioral therapy (CBT)
drug therapy ---- should last a least 6-9 months |
Obsessive compulsive disorder
characteristics |
Potentially disabling condition
persistent obessions --recureent, persisstsnt thought/impulsive/image compulstions - ritualized behavior |
Obsessive compulsive disorder
treatment |
Behavioral therapy
drug therapy --- SSRIs |