Peptic Ulcer Disease

Diseases of the stomach lecture notes

14 cards   |   Total Attempts: 188
  

Cards In This Set

Front Back
Question 1
This comes from a patient who has stomach pain after taking a bottle of Advil and a fifth of vodka.
What is this?
Acute gastritis
Name 3 categories (and examples) of etiologies of chronic gastritis
Chronic infection: H. pylori
Autoimmune: Assoc. w/ pernicious anemia
Toxic: Alcohol, smoking
Question 3
What is the organism seen here?
H. pylori
Name 5 conditions associated with H. pylori
Chronic gastritis
gastric ulcers
duodenal ulcers
MALT lymphoma
Adenocarcinoma
What are the two 1st line drugs to treat H. pylori?
Which is preferred when resistance is not a factor?
What is second line?
Answer 5
Clarithromycin and metronidazole
Clarithromycin is used unless resistance is >15%
Whichever of the two 1st line drugs you haven't tried yet
Question 6
What is this?
Chronic gastritis
Which cells and regions of the stomach are affected in autoimmune chronic gastritis?
Parietal cells
Body and fundus (b/c that is where parietal cells are)
Name at least 3 things different in environmental chronic gastritis compared to autoimmune
Affects the antrum as well as the body
decreased G cells --> low gastrin and hypochlorhydria
not associated with antibodies or pernicious anemia
It is associated with ulceration (auto is not)
What is the difference between reactive gastropathy and gastritis?
There is hemorrhage but minimal inflammation in reactive gastropathy (causes are similar)
What are the most common sites of peptic ulcers?
(In order from most to least common)
Duodenum, first portion
Stomach (antrum)
GE junction (reflux, Barrett's)
Within margins of a gastrojejunostomy
In the duodenum, stomach, and/or jejunum in Z-E syndrome
Within or next to an ileal Meckel diverticulum that contains ectopic gastric mucosa
Question 11
What is this?
Peptic Ulcer
What blood type is associated with an increased risk of H. pylori infections and resultant diseases?
Type O
Question 13
What is shown in the center of this image just above the forceps?
Penetrating acute duodenal ulcer
What causes Zollinger-Ellison syndrome?
Pancreatic or duodenal tumor causes hypergastrinemia, resulting in extremely high acid production. This leads to multiple ulcers (rather than the usual solitary ulcer) that are usually unresponsive to therapy.