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"Juvenile Diabetes"
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Type I
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"Adult-onset Diabetes"
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Type II
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Explain cycle of Type I diabetes
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Autoimmune response kills Beta Cells--->No Insulin-->High Glucose in blood exceeds kidney limits-->Glucose leaves in urine/water & electrolytes follows-->(osmotic diuresis)-->cells starving causes liver to release glycogen & breakdown fats--->more glucose & ketones in blood -->ketoacidosis
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90-95% of all Diabetes is this type. Usually associated with ____
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Type II / Obesity (80%)
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Which type makes insulin? Which type doesn't?
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Type II / Type I
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Explain why stress increases abdominal weight gain?
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Stress increases Cortisol release which increases Insulin release (Insulin inhibits the breakdown of stored glucose, fat, protein)
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What are the 4 hormones that oppose insulin?
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Glucagon (Alpha Cells), Cortisol (Adrenals), Epinephrine (Symp. NS), Growth Hormone (Pituitary)
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Type II diabetes is usually treated with these 3 things
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Diet, Exercise, Oral Meds (Hypoglycemics or Insulin)
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What is the major physiological difference between Type I and Type II diabetes?
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The pancreas makes some insulin in Type II and none in Type I
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With Type II diabetes, what Insulin levels and Glucose levels would be seen? Type I?
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High Insulin (eventually) and High Glucose / Low Insulin and High Glucose
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How does the liver contribute to the dysfunction in Type II diabetes?
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Produces glucose haphazardly (to blood stream) despite high levels already present
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Besides obesity or race, you have a risk of developing Type II diabetes if your BP is ____, your HDL is ____, your triglycerides are _____, your age is ____
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>= 140/90 / <=35 / >=250 / 45+
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Ethnicities prone to Diabetes Mellitus (5)
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African American, Asian American, Native American, Latino, Pacific Islanders
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Diabetes Diagnostics: Positive fasting glucose level? Positive Random glucose level? Two-hour postload glucose tolerance test level?
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>= 126 / >=200 / >=200
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Why are elderly more prone to diabetes development?
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Age-related elevation of blood glucose & coexisting illness (HTN, HD, Stroke, etc.) complicating management.
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