Front | Back |
What are the most common malignancies of the lower female tract in order?
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1. endometrial ca2. ovarian ca3. cervix
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Most common cause of death in women due to gynecologic neoplasm in the US?
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Ovarian ca - since most often diagnosed at a later stage after metastasis
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Age at which ovarian ca probability markedly begins to increase
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50
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What are cell lines present in ovarian tissue?
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- epithelial
- germ cells or sex cord - stromal cells |
What are the types of ovarian ca arising from the epithelial cells?
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Serous
mucinous endometrioid brenner carcinosarcoma or mixed mesodermal tumors |
What are the types of ovarian ca arising from the germ cells?
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Teratoma - mature and immature
dysgerminoma embryonal carcinoma choriocarcinoma endodermal sinus tumor mixed germ cell tumor |
What are the types of ovarian ca arising from the gonadal stroma?
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Granulosa-theca cell tumors
sertoli-leydig tumors gynandroblastomas lipid cell tumors |
Neoplasms derived from non specific mesechyme
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Fibroma, hemangioma, lipoma
lymphoma sarcoma |
Neoplasms metastatic to the ovary
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GI (stomach primary=Krukenberg
breast endometrium lymphoma |
Mean age at diagnosis of ovarian ca?
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60
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What is the life time risk of obtaining ovarian ca?
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1.8%
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What is the life time risk of obtaining ovarian ca with a personal history of breast ca or a first degree relative with ovarian ca?
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4-7%
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