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Aminoglycoside
(ending) |
-mycin
|
Aminoglycoside
drug class |
Antiinfective
bactericidal |
Aminoglycoside
DRUGS |
-gentamicin (Garamycin)
-streptomycin- can sometimes be used for TB -tobramycin (Nebcin) -amikacin (Amikan) -kanamycin (Kantrex) -neomycin |
Aminoglycoside
Adverse Effects |
Ototoxicity- vertigo, tinnitus, balance problems, hearing loss
nephrotoxicity- monitor renal fxn tests: bun, creatinine, creatinine clearance, I &O’s neurotoxicity/ neuromuscular blockade- observe for headache, lethargy, tremor, paresthesia |
Aminoglycoside
Miscellaneous |
Take Peak and Trough
Contraindicated for pts with renal probles, pts taking other ototoxic meds |
Vancomycin
trade name |
Vancocin
|
Vancomycin
Indications |
IV- MRSA
PO- C. diff and Psuedomembranous colitis |
Vancomycin
Adverse effects |
Ototoxicity
Nephrotoxicity Red man syndrome-occurs if vanc is given to quickly, causing itching of head and red rash around neck, face or torso |
Vancomycin
Administration |
Give slowly @A least over 1 hour (minimum)
- Never give IM because it is so harsh and irritating -Watch site of administration for tissue irritation, (high incidence of pain and thrombophlebitis) -*****Must draw blood for drug levels peak and trough***** |
Penicillin
ending |
-cillin
|
Penicillin
|
Short half life so frequent doses required
|
Penicillin
|
-penicillin (Penicillin V Potassium- Pen VEE K)- should be taken on an empty stomach: decreases effectiveness of oral contraceptives
amoxicillin (Amoxil) -ampicillin (Amcil, Omnipen) -Dicloxacillin (Diclox) -nafcillin (Nafcil, Unipen) -Benzylpenicillin, commonly known as penicillin G, is the gold standard type of penicillin. 'G' in the name 'Penicillin G' refers to 'Gold Standard'[citation needed]. Penicillin G is typically given by a parenteral route of administration (not orally) because it is unstable in the hydrochloric acid of the stomach. -ampicilin/claulanate (Augmentin) -ampicillin/sulbactam (Unasyn) -ticarcillin/ clavulanate (Timentin) |
Penicillin
adverse effects |
-Diarrhea, nausea,
-superinfection, -neurotoxicity, -hypersensitivity (allergic rxn), urticaria (hives), rash |
Penicillin
administration |
-penicillins are incompatible with aminoglycosides so do not mix and administer at different sites at least 1 hour apart
-increases the risk for bleeding so use cautiously in person taking anticoagulants -asses iv site for signs of phlebitis |
Cephalosporins (ceph; cef)
1st generation |
First Generation: treat gram pos organism
-Cephalexin (Keflex) -cefazolin (Ancef, Kezol) -cefadroxil (Duracef) |