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Myofilament
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A.) A protein microfilament responsible for the contraction of a muscle cell.
b.) Composed mainly of myosin or actin. |
Thick Filaments
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A.) Each is made of several hundred molecules of myosin.
b.) "Golf club" heads on one half are angled to the right; on the other half they're angled to the left; and have no heads in the middle, which is called a bare zone. |
Myosin
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A.) A protein shaped like a golf clube, with 2 chains intertwined to form a shaftlike tail & a double globular head projecting from it.
b.) Found in thick filaments. |
Thin Filaments
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A.) Composed mostly of 2 intertwined strands of fibrous (F) actin.
b.) Also composed of 40-60 molecules of tropomyosin. |
F Actin
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A protein composed of a string of subunits called globular (G) actin.
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G Actin
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A spherical-shaped protein with an active site.
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Active Site
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The region of G actin that can bind to the head of a myosin molecule.
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Tropomyosin
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A.) A protein that, when the muscle fiber is relaxed, blocks the active sites of 6 or 7 G actins & prevents myosin from binding to them.
b.) Each molecule has troponin bound to it. |
Troponin
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A smaller, calcium-binding protein.
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Elastic Filaments
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A.) Made of a huge, springy protein called titin (connnectin).
b.) They flank each thick filament & anchor it to a structure called the Z disc. c.) Helps stablilize the thick filament, center it between thin filaments, & prevent overstretching. |
A Band
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A dark band formed by parallel thick filaments that partially overlap the thin filaments causing the dark striations.
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I Band
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A light band composed of thin filaments only.
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Z Disc
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A protein disc that bisects each light I band & provides anchorage for the thin filaments & elastic filaments at the ends of sarcomeres that appears as a narrow, dark line in the middle of the I band.
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Sarcomere
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A.) The distance from one Z disc to the next.
b.) The functional contractile unit of a muscle fiber. c.) Causes a muscle to contract by shortening & pulling the Z discs closer to each other. |
T Tubules
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A tunnel-like extension of the sarcolemma extending from one side of the muscle fiber to the other that conveys electrical signals from the cell surface to the interior.
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