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What does the word "double" mean in the double helix Watson-Crick DNA model?
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The "double" in the double helix means that DNA is found in a double-stranded form - 2 single-stranded chains of DNA stuck to each other via hydrogen bonding of the base pairs.
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How are the 2 single-strands in the Watson-Crick model positioned?
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The 2 single-strands are anti-parallel to each other. Going from 5' to 3' of one strand means going from 3' to 5' of the other strand.
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What does the word "helix" mean in the double helix DNA model?
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The "helix" in the double helix means that the entire thing is wound up in a spiral. |
What is the composition of DNA?
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The DNA comprises of purine and pyrimidine bases, sugars, phosphate |
What is the composition of a nucleotide?
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Nucleotide = base + sugar + phosphate = Adenine, Guanine, Thymine, Cytosine.
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What is the composition of a nucleoside?
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Nucleoside = base + sugar = Adenosine, Guanosine, Thymidine, Cytidine.
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How are bases classified?
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Base can either be purines A and G (the big ones with 2 rings) or pyrimidines T and C (the small ones with 1 ring).
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What gives DNA its acidity?
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The phosphate group gives DNA its acidity.
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Describe the base pairing specificity.
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Base pairing specificity: A with T, G with C |
How many hydrogen bonds does A form with T?
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A forms 2 hydrogen bonds with T
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How many hydrogen bonds does G form with C?
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G forms 3 hydrogen bonds with C.
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Which of the two types of bonds (AT or GC) are stronger?
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GC bonds are stronger. DNA with high GC content will be harder to break apart
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What type of strands of DNA hydrogen bond with each other?
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Complementary strands of DNA hydrogen bond with each other.
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5'-ATGC-3' will be complementary to which strand of DNA?
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5'-ATGC-3' will be complementary to 5'-GCAT-3' or 3'-TACG-5', but NOT 5'-TACG-3'.
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How does DNA can transmit genetic information?
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Because of the complementary nature of base pairing, DNA can transmit genetic information through replication.
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