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What are double ringed nitrogenous bases called, and what are they?
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Purines/ guanine and adenine
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What are single ringed nitrogenous bases called, and what are they?
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Pyrimidines/ cytosine and thymine (they all have ''y's")
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What is the name of the rule that refers to the complementary nature of DNA? (Number of Adenine = Number of Thymine and Number of Cytosine = Number of Guanine)
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Chargaff's Rule
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The process of DNA making a copy of itself is called
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Replication; average speed: 20 nucletides per second are added to new strand
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When replication is completed, each molecule will have one original template strand. This is called
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Semi-conservative replication
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In DNA replication, new strands always begin at its __ end and nucleotides are added to its __ end.
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5' , 3'
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Enzymes responsible for building a DNA polymer; there are more than one kind; they catalyze the addition of nucleotides to the 3' end of the strand and cannot start the strand
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DNA polymerases
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Molecules in the nucleus that provide the substrates to build a new strand of RNA or DNA; have 3 phosphate groups
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Free nucleotides
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Specific sequences on the DNA template strand where replication begins
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Origin of replication
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Giant cloud of molecules that contain all enzymes, all substrates, and everything needed for replication --moves along the DNA molecules--replication only occurs where this is
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DNA replication machine
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Enzyme responsible for pulling the DNA helix apart; breaks hydrogen bonds
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DNA helicase
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Proteins that bind to the strands, keeping them apart so replication can occur
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Single-strand binding proteins
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Point where the two template strands of DNA are being pulled apart (y-shaped structure)
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Replication fork
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New strand built in the same direction that the replication fork is moving
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Leading strand
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New strand built in the opposite direction of the movement of the replication fork
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Lagging strand
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