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Functions of Blood
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1. Transports gases and nutrients
2.Regulation of PH and osmosis 3.Maintenance of Body temperature. 4.Protection against foreign substances 5.Clot Formation |
Composition of Blood
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55% Plasma - 91 % water 7 % proteins
45 % formed elements |
Plasma
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Liquid Part of Blood
Ions Nutrients Waste Products Gases Regulates Substances - hormones, enzymes |
Proteins of Plasma
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Albumins - Viscosity, Osmotic Pressure, Buffer, Transports Fatty Acids, Free bilirubin, thyroid hormones
Globulins - Transports Lipids, Carbohydrates, Hormones, Ions, Antibodies Fibrinogen - Blood Clotting |
Red Blood Cells (erythrocytes)
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Contains Hemoglobin, Transports oxygen and carbon dioxide
1/3 Hemoglobin 2/3 Lipids RBCs last 120 days in circulation |
White Blood Cells (leukocytes)
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Protects body against microogranisms and remove dead cells and debris
Granulocytes - Cytoplasm contains large granules, have multi lobed nuclei. Has 3 distinctive types : Neutrophils, eosinophils, basophils O |
Platelets (thrombocytes)
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Form Platelet plugs, release chemicals necessary for blood clotting
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Hematopoiesis
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Process of Blood Cell Production
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Carbon Dioxide from tissues to lungs
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7 % dissolved in plasma
23 % in combination with hemoglobin 70 % transported as bicarbonate ions produced as a result of combination of H20 and Co2 because of enzyme carbonic anhydrase found within RBCs |
Erythropoietin
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A hormone that stimulates RBC production. Produced by kindeys in response to low blood 02 levels |
Hemoglobin Breakdown
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Broken down by macrophages into heme and globen chains
Globen chains of hemoglobin are broken down to amino acids and are metabolized or used to build new proteins |
White Blood Cells other questions
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Ameboid - pseudopodia make them move like amoeba
Diapedesis - cells become thin, elongate and move either between or through endothelial cells of capillaries Chemotaxis - attraction to and movement toward foreign materials or damaged cells |
Neutrophils
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Secrete Lysozome
Accounts for 60-70 % of WBC |
Eosinophils
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Enter tissues during inflammatory response.
prevelant in allergic reactions and parasitic infections 2-4 % of WBC |
Basophils
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Inflammatory and allergic reactions
Produce histamine and heparin Less than 1 % of the WBC population |