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Cards In This Set
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Heritable change in genetic material- can occur in "open reading frame" (ORF) or in regulatory region of DNA
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Mutation
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Process that leads to new combinations of genes on a chromosome
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Recombination
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Piece of DNA which codes for one product. Ex: protein
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Gene
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Genetic characteristics of an organism
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Genotype
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Visible characteristics of an organism
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Phenotype
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Natural errors in DNA replication. Rate is very low- one in a million genes.
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Spontaneous Mutation
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A chemical, physical or biological agent which increases mutation rate
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Mutagen
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This type of mutation is caused by a mutagen
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Induced Mutation
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2 Types of Mutations:
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Point Mutations and Frame Shift Mutations
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A type of mutation where base pair sequence is altered (base substitution mutation)
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Point Mutation
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3 Types of Point Mutations
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Silent Mutation,
Missense Mutation, Nonsense Mutation |
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Type of mutation:
alteration in base pair- results in same amino acid being coded. Ex: wildtype GCU (ala) -> CCC (ala) -not noticed & neither good/nor bad |
Silent Mutation
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Type of mutation:
-alteration in base pair resulting in different amino acid being coded (or amino acid change) -protein structure may or may not be affected |
Missense Mutation
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A missense mutation where GCU (ala) -> GGU (gly) are chemically similar and the overall structure of the protein is not affected, is an example of a ______ mutation.
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Neutral Mutation
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A Neutral Mutation is analogous to a ______ Mutation.
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Silent Mutation
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