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Cards In This Set
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Immunologic Diseases branch into what 3 branches
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Hypersensitivities / Autoimmune / Immunodeficiency
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Hypersensitivity branches into what 4 types.... describe each
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Type I : Immediate IgE-Mediated
Type II: Cytotoxic Type III: Immune-Complex-Mediated Type IV: Delayed Type Cell-Mediated |
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Immunologic Disease caused due to overreaction of the immune system upon repeated exposure to antigen
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Hypersensitivity
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Immunologic Disease which is a reaction of the immune system against self antigens
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Autoimmune
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Immunologic Disease that is an underreaction of the immune system
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Immunodeficiency
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When IgEs bind to Mast Cells after first exposure it is called ______? What type of Hypersensitivity is this?
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Sensitization / Type I
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The after sensitization reaction in Hyper Type I is called
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Anaphylaxis
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1st exposure causes _____ of B cells and production of ______ in a T- _________ manner.
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Activation / IgE Antibodies / Dependent
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What happens to IgE's after they are produced by plasma cells in 1st exposure?
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They bind to Mast Cells
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2nd exposure causes antigen to bind to _______ on _____ cells. These cells then _______ and release ______
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IgE antibodies / Mast Cells / Burst / Inflammation Mediating Chemicals (Histamine, ex.)
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What are the 3 Localized Anaphylaxis (Type I) listed? Systemic Anaphylaxis (3) ?
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Localized : Asthma, Hay Fever, Hives / Systemic: Shock, Peanut, Bee Stings
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The release of Histamine is called ________
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Degranulation
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Hives is called ______. It is caused by an allergen that is ______. It causes the skin condition of _____ and _____. Mast cells release ______. Treatment is _______ , like _______ for example
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Urticaria / Ingested / Wheal and Flare (rash) / Histamine / Antihistamine / Benadryl
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Hay Fever is called _________. It is caused by an allergen that is _______. It causes ________. Mast Cells release ______. Treatment is _____, like ______ for example
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Allergic Rhinitis / Inhaled / Itchy watery eyes, sneezing, runny nose / Histamine / Antihistamine / Benadryl
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In systemic anaphylaxix, allergen enters ____ and becomes _____. This can induce _____. Treatment is ________ which ________. Examples are (3)?
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Bloodstream / systemic / Shock / Epinephrine Injections / Constrict Blood Vessels (raises BP) / Bee Stings, Peanuts, Penicillin
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