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Drugs that reduce lipid levels
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Antilipemic Drugs
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The protein components of lipoproteins
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Apolipoproteins
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A fat-soluble steroid found in animal fats, oils, and egg yolk and widely distributed in the body especially in the bile, blood, brain tissue, liver kidneys, adrenal glands, and myelin sheaths of nerve fibers
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Cholesterol
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Microscopic droplets made up of fat and protein that are produced by cells in the small intestine and released into the bloodstream. Their main purpose is to carry fats to the tissues throughout the body, primarily the liver
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Chylomicrons
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Chylomicrons consist of about ____% _______ and small amounts of ____, _____, and ______
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90% triglycerides / Cholesterol, Phospholipids, Proteins
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Lipids originating outside the body or an organ
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Exogenous Lipids
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The characteristic initial lesion of atherosclerosis, also known as a 'fatty streak'
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Foam cells
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A class of cholesterol-lowering drugs that work by inhibiting the rate-limiting step in cholesterol synthesis; aslo commonly referred to as 'Statins'
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Hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase Inhibitors
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A condition in which higher than normal amounts of cholesterol are present in the blood.
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Hypercholesterolemia
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A conjugated protein synthesized in the liver that contains varying amoun ts of triglycerides, cholesterol, phospholipids, and protein;
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Lipoprotein
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A class of cholesterol-lowering drugs that are more formally known as HMG-CoA reductase inhibitors
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Statins
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Compounds that consist of fatty acids and a type of alcohol known as glycerol. These are the principal lipids in the blood.
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Triglycerides
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Triglycerides, circulating in the blood, bind to proteins forming either ______ or _____
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High-Density Lipoproteins (HDL) / Low-Density Lipoproteins
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The two primary forms of lipids in the blood
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Triglycerides and Cholesterol
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_______ function as an energy source and are stored in adipose fat tissues. _______ is primarily used to make steroid hormones, cell membranes, and bile acids
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Triglycerides / Cholesterol
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