Lilly: Ch. 26 \"Coagulation Modifier Drugs\"

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Substances that prevent or delay coagulation
Anticoagulant Drugs
Drugs that prevent the lysis of fibrin and in doing so promote clot formation? What is another name for them?
Antifibrinolytic Drugs / Hemostatic Drugs
Substances that prevent platelet plugs from forming. Ex?
Antiplatelet Drugs / Aspirin
A substance that inactivates three major activating factors of the clotting cascade (factor II 'thrombin', factor X, factor IX)
Antithrombin III
Insoluble solid elements of blood that have chemically separated from the liquid component of the blood
Clot
The process of blood clotting
Coagulation
The series of steps beginning with the intrinsic or extrinsic pathways of coagulation and proceeding through the formation of a fibrin clot
Coagulation Cascade
The formation of a thrombus in one of the deep veins of the body (usually the leg)? Which veins are most affected by this?
Deep Vein Thrombosis / Iliac & Femoral Veins
A blood clot (thrombus) that has been dislodged from the wall of a blood vessel and is traveling throughout the bloodstream
Embolus
A protein molecule that catalyzes chemical reactions of other substances without being altered or destroyed
Enzyme
A stringy, insoluble protein produced by the action of thrombin on fibrinogen during the clotting process
Fibrin (a major component of blood clots/thrombi
A plasma protein that is converted into fibrin by thrombin in the presence of calcium ions
Fibrinogen
The continual process of fibrin decomposition produced by the actions of the enzymatic protein fibrinolysin. It is the normal mechanism for removal of small fibrin clots and is stimulated by anoxia, inflammatory reactions, and other kinds of stress
Fibrinolysis
An area of the circulatory system under going fibrinolysis
Fibrinolytic System
A rare, inherited blood disorder in which the blood does not clot normally
Hemophilia