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Drug that primarily cuases arterial and venous dilation through their action on peripheral sympathetic neurons
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Alpha1 Blockers
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Medicines used to treat hypertension
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Antihypertensive Drugs
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The amount of blood ejected from the left ventricle, measured in L/min
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Cardiac Output
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Drugs that modify the function of the sympathetic nervous system in the brain by stimulating alpha2 receptors which are inhibited in nature and thus have a reverse sympathetic effect and cause decreased BP
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Centrally-acting Adrenergic Drugs
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Elevated systemic arterial pressure for which no cause can be found; also called primary or idiopathic hypertension
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Essential Hypertension
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A common, often asymptomatic disorder in which systolic blood pressure persistently exceeds 140 mm HG and/or diastolic pressure exceeds 90 mm HG
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Hypertension
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Sudden drop in BP upon changing positions, especially when standing from seated position
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Orthostatic Hypotension
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A drug that is inactive in its given form, and which must be metabolized to its active form in the body, generally by the liver, to be effective
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Prodrug
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High BP caused by another disease such as renal, pulmonary, endocrine, or vascular disease
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Secondary Hypertension
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What is the largest risk factor for cardiovascular disease, heart failure, stroke
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Hypertension
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Blood pressure is computed with what 2 elements
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Cardiac Output x Systemic Vascular Resistance (SVR)
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Untreated hypertension causes risk to what organs? (4)
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Heart, brain, kidneys, and eyes
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In patients with diabetes or renal disease, the normal BP goal is lower... what is it?
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130/80 mm Hg
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Potassium-wasting diuretics are called ____
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Loop Diuretics
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Which antihypertensive drugs do NOT have an impact on vasodilatory action
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Diuretics
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