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Cards In This Set
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The most common antibody produce in primary response to antigen
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IgM
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Important antibody as an antigen receptor on Bcell
what are immunoglobulines
what part of immunolglubulin determine the antibody type
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IgD
they are glycoprotein produced by plasma celss
the heavy chain determin the antibody tpe
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Antibody important in imunity of newborns
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IgA and IgG
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List 3 functions of immunoglobulins
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Binds antigen epitope, fixes complement and opsonizes
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What antibody crosses placenta
through what receptor
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IgG
FCy
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Which subcalss of igG easly crosses placenta
which ones do not cross well
all igG fixes complement except
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IG1 and IG3
ig2 and ig4
IG4
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The perceng of igG in subclasses
true of false, igD fixes complement
rank the antibodies in relation to their aabundance
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IgG1 60% igG2 30% igG3 7% igG4 3%
false igD do not fix complement
igG>igA>igM>igD igE is the lease common
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How does IgE fight parasite
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By binding of eosinophil to igE, if not, nothing happens
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Which class of antibody has polymeric forms
which ones have j joining chain
which one has secretory component
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IgM pentamers and igA dimers
Ig M and A
only igA
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Isotype
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Determinants present on all molecules of each class & subclass of Ig heavy chains and light chain• All healthy members of a species have each isotype
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Genetic variation between individuals within a species, involving different alleles at a given locus
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allotype
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Example of allotype
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ABO blood system
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Idiotype
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Variations in V domain Determine binding specificity,can act as Ag
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Which T helper cells regulate cellular immunity and which regulate humoral immunity
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TH1 is for cellular immunity
TH2 is for humoral immunity
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Which Thelper cell regulate delayed hypersensitvity
which one regulate macrophage
which one regulate allergic response
whic regulate antibody
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TH1
TH1
TH2
TH2
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