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Cards In This Set
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Fc receptor
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Phagocyte receptor capable of recognizing antibodies bound to Bacteria
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Phagosome
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Intracellular pod that contains the engulfed particle within phagocyte that lysosome fuses with to degrade particle
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Toll Like Receptors (TLR)
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Recognize Pathogen Associated Molecular Patterns (PAMPs), composed of lucine rich repeats. Located on cell membrane and also on endocytic vesicles where they determine the degradation of foreign pathogens. Also cause the release of cytokines and chemokines.
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TLR-9
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Recognize unmethylated CPG-islands once bacterium is degraded within the cell
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TLR-5
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Toll Like Receptor- recognizes Flagellum
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TLR-3
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Recognizes DsRNA (viruses)
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Cytokine
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Cell movement. any secreated protein that affects nearby cells bearing receptors. Secreated by macrophages. Initiate inflammation. Also called interleukines. (IL-2) = interleukin 2
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TLR-4
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Recognizes lipopolysaccharide (LPS) or gram (-) bacteria
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Lipopolysaccharide (LPS)
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Component of gram negative bacteria
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Nucelotide Oligliomerization Domain (NOD)
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Intracellular receptors that recognize foreign pathogens such as viruses or intracellular bacterium that live in the cytosol. REcognize bacterial wall peptidoglycans and induce secretion of inflammatory cytokines, antimicrobial products
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RIG-I-like helicases (RLH)
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Intracellular receptor that recognizes viral dsDNA with its RNA helicase domain that acts as a trascription factor to produce interferons.
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Immunogen
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A substance that can elicit and immune response is immunogenic. All immunogens are antigens
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Antiserum
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The blood serum of a immunized individual. Contains antibodies that are specific to the immunogen
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Sero-conversion
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When you have developed detectable Ab in blood (serum) to the immunogen (HIV
home test)
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Adjuvants
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Agent that modifies the effect of other agents, such as a drug or vaccine.
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