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Processed peptides bound to MHC molecules
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T cell antigens
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Recognition by T cells of peptides bound to one's own MHC
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MHC restriction
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Cells that capture and present peptides to T cells
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APC
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Dendritic cells, macrophages, B cells
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Professional APC
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Another name for immature dendritic cell in the skin
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Langerhans cells
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Transports antigen from epithelia to draining lymph node
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Dendritic cell
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Destination of antigens captured in epithelia and sub-epithelial tissues
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Lymph nodes, MALT, GALT, BALT
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Destination of blood borne antigens
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Spleen
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Microbial-indcuced activators of dendritic cells
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TNF, IL-1, TLR signaling
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Destination of dendritic cells in lymph nodes
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T cell zones
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Chemical signal that attracts activated dendritic cells to draining lymph node
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Chemokines that bind to CCR7 on dendritic cell
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Afferent lymphatic vessel -lymph node - efferent lymphatic vessel
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Flow of lymph through a draining lymph node
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Human major histocompatibility complex (MHC) proteins
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Human leukocyte antigens (HLA)
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Genes that encode the Class I MHC moleucules
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HLA -A.B,C
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Cells that express class I MHC molecules
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All nucleated cells
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