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What is the Innate Defense of the Immune System?
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Non-Specific defense
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What are the two types of innate defenses?
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1) Surface Barriers 2) Internal Defenses
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What type of defense is the surface barrier considered?
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The first line of defense
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What are the four factors in the surface barriers, or the first line of defense?
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1) Cutaneous membrane (The Skin) 2) Mucous membranes 3) Acidity of secretions 4) Enzymes
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How is the cutaneous membrane (skin) a line of defense?
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The skin has an outer layer of protective keratin
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How do the mucous membranes provide a line of defense?
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They produce mucous secretions that contain protective chemicals to trap microbes, also contain cilia that sweep trapped particles out of body
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Which secretions are acidic, and how do they protect the body?
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Acidic pH of sweat and HCl in gastric secretions, acidity kills microbes
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What is the acid mantle?
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The acidity of perspiration
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What enzymes provide defense for the body?
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Lysozymes found in tears and salivia
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What is another name for the internal defense of the body?
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The second line of defense
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What are the 5 factors of the internal defenses, or the second line of defense?
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1) Phagocytes 2) Natural Killer (NK) cells 3) Inflammation 4) Antimicrobial proteins 5) Fever
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What are phagocytes?
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A general name for cells that capture and destroy pathogens
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What are the 3 types of phagocytes?
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1) Macrophages 2) Neutrophils 3) Eosinphils
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What are macrophages?
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Derived from blood monocytes and are known by different names based on specific location
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What are the two types of macrophages
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1) Free macrophages 2) Fixed macrophages
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