Front | Back |
List the primary factors determining the O2 delivery to tissues
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Macro: CO, Hgb conc, O2 sat
Micro: periph shunting,k |
What leads to the occurence of hypovolemic shock?
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Inadequate INTRAVASCULAR volume to meet O2 and metabolic needs
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What is the role of vasopressors?
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They modulate vasoconstriction and increase BP
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What is the role of inotropes?
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They increase cardiac performance and thereby improve CO
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What major interventions will improve O2 delivery?
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Resore balance to 1)the pump (CO) 2)the transport system (periph circ) and 3)the transport medium (blood)
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What can cause shock?
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-decrease in CO
-vasodilation -low circulating blood volume |
What 4 major ways can plasma volume be decreased leading to hypovolemic shock?
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Loss of fluid from vascular to ext enviro
-hemorrhage Loss of fluid from vasc to interstitial space -decreased plasma protein (burn, kidney/liver disease) -increased capillary perm (sepsis, prolonged ischemia, burn) |
Highest osmolarity?
5 dextrose .9 NaCl 3NaCl 5alb |
3%NaCl
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Cause fluid to move from intracell to extracell?
5 dextrose .9 NaCl 3NaCl 5alb |
3% NaCl
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Most hypotonic?
5Dext 5Det/halfNS 3NaCl 5Alb |
5% Dextrose
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What is distributive shock?
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Periph tissues not being perfused
-anaphylactic, neurogenic, septic |
List the major fluid compartments in the body
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Intracellular, extracellular (composed of intravascular and interstitial)
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Compare the size of body fluid compartments
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Body is 60% water (42L)
Intracellular is 2/3rd of total body water (28L) Extracellular is 1/3 of total body water (14L) -Interstitial is 3/4 of extracellular volume (10.5L) -intravascular is 1/4 of extracellular volume (3.5L) |
Define osmotic
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Micro force for fluid movement accross cell membrane
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Units of:
osmolality osmolarity |
MOsm/kg (measured)
mOsm/L (Calclulated) |