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During the hemostatic process, plts interacting with and binding other plts is referred to asa. adhesionb. aggregationc. released. retraction
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B. aggregation
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Which of the following therapeutic agents inhibits coagulation by inhibiting plat function?a. aspirinb. coumadinc. heparind. streptokinase
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A. aspirin
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Which of the following is part of primary hemostasisa. fibrinolysisb. blood vesselsc. intrinsic systemd. extrinsic system
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B. blood vessels
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A defect in plt response to injury or a dec in plt conc often results ina. musculoskeletal bleedingb. mucosal membrane bleedingc. hemarthrosesd. none of the above
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B. mucosal membrane bleeding
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What is the anticoagulant of choice for routine coagulation testing?a. heparinb. 3.2% Na citratec. 3.8% Na citrated. Na oxalate
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B. 3.2% Na citrate
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The ratio of anticoagulant to blood for coagulation procedures should bea 1:4b. 1:7c. 1:9d.1:10
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C. 1:9
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Which of the following factors demonstrates a sex linked inheritance patterna. factor Vb. factor VIIIc. factor Xd. vWF
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B. factor VIII
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What would be the expected PT and PTT test results for a pt with a fibrin stabilizing factor def?a. PT prolongedb. aPTT prolongedc. PT and aPTT prolongedd. PT and aPTT normal
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D. PT and aPTT normal
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Which of the following aids in preventing excess clottinga. thrombinb. factor VIIc. nitric oxided. protein C
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D. protein C
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What is the role of Vitamin K in relation to the vit K dependent group of clotting factors?a. Vit. K is converted into various pro-coagulantsb. vit. K binds CA++ to activate pro-coagulantsc. vit. K carboxylates pro-coagulants to functional formsd. vit. K regulates production of dependent factors
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C. vit. K carboxylates pro-coagulants to functional forms
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What are the primary roles of vWFa. mediate plt adhesion and carrier molecule for factor VIIIb. mediate plt adhesion and carrier molecule for factor IXc. inhibits excess coag and activates protein Cd. activate plasmin and enhances vit. K factors
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A. med. plt adhesion and carrier molecule for factor VIII
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Fibrin strands are crosslinked and the fibrin clot stabilized by the activity of a. alpha 2 antiplasminb. factor XIIIac. plasmind. thrombin
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B. factor XIIIa
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Which of the following enzymatically degrades the stabilized fibrin clot?a. plasminogenb. plasminc. prothrombind. thrombin
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B. plasmin
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Unfractionated heparin works as an inhibitor to clotting in the body by:a. chelating calcium ionsb. preventing activation of prothrombin c. antagonizing vitamin K's role in factor synthesisd. enhancing the neutralizing effects of naturally occurring anti-thrombin
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D. enhancing the neutralizing effects of naturally occurring anti-thrombin
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Measurement of the time required for fibrin formation when thrombin is added to plasma evaluates thea. fibrinogen concb. prothrombin concc.extrinsic clotting systemd.intrinsic clotting system
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A. fibrinogen conc
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