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What size and chromicity are the RCs in iron deficiency anemia? What are the abnormal cell shapes?
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Microcytic, hypochromic; elliptocytes & target cells
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What size & chromicity are the RCs in anemia of chronic disease?
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Microcytic, normochromic
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What 2 hormones/proteins are assoc w/ the pathophys of anemia of chronic disease?
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Hepcidin & lactoferrin
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What size & chromicity are RCs in sideroblastic anemia?
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Microcytic, hypochromic
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What abnormal cell shape is assoc w/ sideroblastic anemia? inclusions?
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Target cells, pappenheimer bodies, basophilic stippling
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If megaloblastic anemia is caused by a vitamin B12 def, what is the specific name for this disorder?
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Pernicious anemia
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What size are RCs in megaloblastic anemia?
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Macrocytic
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What abnormal cells are assoc w/ megaloblastic anemia? inclusions?
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Hyperseg neuts, lg plts, all inclusions except Heinz bodies
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Does megaloblastic anemia affect all cell lines? What is the term for this?
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Yes, pancytopenia
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What is aplastic anemia? Are all cell lines affected?
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BM is mostly fat, doesn't produce many cells; yes, pancytopenia
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A rare form of hereditary aplastic anemia is specifically called what?
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Fanconi's anemia
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What is pure RC aplasia?
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BM is normal, but RC production is severely decreased
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What is the specific name of the anemia assoc w/ erythropoietin resistant stem cells (RC aplasia)?
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Diamond-blackfan anemia
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What are the 3 types of hemolytic anemias assoc w/ cytoskeletal defects?
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Hereditary spherocytosis, H elliptocytosis, H stomatocytosis
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What is the RC size & chromacity when there is hereditary spherocytosis?
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Microcytic, HYPERchromic
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