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In AIHA, what is approach if severe anemia and no compatible blood?
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Give ABO/Rh matched, that's fine
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What is most common toxicity of bortezomib?
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Neuropathy
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What is inheritance of G6PD?
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X-linked so should go from mom to son
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What pathological finding is seen in WBC in AML?
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Auer rods
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What are treatments for PV?
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Phlebomtomy (< 45 for men, < 42 for women)+ low dose ASA, hydroxyurea if phlebotomy not able to be performed or fails or plt > 1. 5million
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Which disease affects both PTT and bleeding time?
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VWD disease
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How does TRALI present?
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Within 6 hours of transfusion usually associated with plasma
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What is prophylactic therapy for SC dz with stroke?
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Monthly erythrocyte transfusions (2 units)Why? 70% probability of recurrence; transfusions reduce that by 50% (down to 35%)
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What is rx of choice for Waldenstroms?
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Rituximab
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How do you treat a patient perioperatively with ET?
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Platelet apheresis followed by hydroxyurea post op
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How do you treat pure red cell aplasia (e.g. HIV with parvovirus)?
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Transfusion and IvIg
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