Front | Back |
What are the two types of neuronal networks in the intestinal tract? Location? Function?
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1. Submucosal plexus (under mucosa); secretion
2. Myenteric plexus (between muscles layers); motility
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Motility of the GI tract is done by what two muscles?
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1. Circular (closer to lumen)
2. Longitudinal (under serosa; outer)
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The autonomic nervous system consists of what in the GI tract?
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Intrinsic (Enteric)
Extrinsic (Autonomic)
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Parasympathetic innervation from what two nerves?
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Vagus (upper GI), pelvic (lower GI)
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What are the presynaptic parasympathetic gangions and their functions?
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1. Myenteric: contraction (b/t muscles)
2. Submucosal; secretion
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Postsynaptic parasympathetic neurons release what?
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ACh or peptide
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Parasympathetic is mostly what type of information (i.e. afferent or efferent)?
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75% afferent
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T/F: The submucousal and myenteric plexus receive information from the sympathetic and parasympathetic postganglionic nerves.
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T
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Source/function of ACh?
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Cholinergic cells
Contract smooth muscles, relax sphincters
Increase salivary, gastric, pancreatic secretion
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Source/function of norepinephrine
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Adrenergic neurons
Relax smooth muscle; contract sphincters
Increase salivary secertion (same as ACh)
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VIP source/function
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Neurons of mucosa/smooth muscle
Relax smooth muscle
Increase intestinal and pancreatic secretion
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Gastrin-release peptide (GRP) source/function
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Neurons of gastric mucosa
Increase gastrin secretion
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Enkephalins; source/function
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Contract smooth muscle; decrease intestinal secretion
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Neuropeptide Y source/function
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Neurons of mucosa/smooth muscle
Relax smooth muscle
Decrease intestinal secretion
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Substance P: source/function
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Co-secreted with ACh
Contraction of smooth muscle; increased salivary secretion
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