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Acceptance and commitment therapy (ACT)
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CBT intervention designed to help people stay focused and in touch with the present moment; acceptance of negative emotions encouraged as a method to defuse them.
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Accomodation
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Process by which patients’ relatives or significant others collude with them to help them avoid anxiety-provoking situations or repeatedly reassure them that everything is okay; associated with poorer patient outcomes.
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Agoraphobia
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DSM-5, ICD-10, and ICD-11 disorder diagnosed in people who fear being in situations where they may have an intense and embarrassing fear reaction (such as a panic attack) and won’t be able to escape.
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Anterior cingulate cortex
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Front area of cingulate cortex that is important in decision-making, anticipating rewards, emotion, and impulse control.
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Anxiety
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An emotion characterized by feelings of tension, worried thoughts, and physical changes like increased blood pressure; involves cognitive appraisals related to more basic fear responses.
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Anxiolytics
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Drugs used to relieve anxiety; usually refers to benzodiazepines.
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Augmenting agents
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Secondary drugs used to improve the impact of primary drugs; for example, benzodiazepines are sometimes used to augment the effect of SSRIs for OCD.
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Avoidance model of worry
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Cognitive explanation of anxiety that maintains people are often anxious about negative events potentially befalling them in the future; worry about events that haven’t happened yet is negatively reinforced because thinking about anxiety-provoking possibilities is less stressful than experiencing more intense physiological symptoms of anxiety.
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Barbiturates
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Highly addictive sedative-hypnotic drugs such as secobarbital and pentobarbital; previously used as anti-anxiety drugs, but have generally been replaced by benzodiazepines.
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Beta blockers
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Blood pressure reducing drugs that block norepinephrine receptors; used to relieve anxiety.
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Body dysmorphic disorder (BDD)
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DSM-5 and ICD-11 disorder in which people display obsessional preoccupation with one or more perceived physical flaws in their appearance; listed as a variant of hypochondriasis in the ICD-10.
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Buspirone
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An anxiolytic drug that decreases serotonin levels, but not by blocking serotonin reuptake; thus, it is not classified as an SSRI.
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Catastrophic misinterpretation model of panic disorder
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Holds that people prone to recurrent, unexpected panic attacks catastrophically misinterpret certain bodily sensations; the more they interpret sensations in an anxious way, the stronger the sensations become—eventually resulting in a full-blown panic attack.
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Compulsions
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Behaviors or mental acts that a person feels driven to perform.
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Corticostriatal pathophysiological models
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Models that hold that OCD is explicable in terms of the complex circuitry by which various areas of the brain communicate.
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