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Related Flashcards
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Cards In This Set
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Acetylcholine
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The neurotransmitter substance that is released at the synapses of parasympathetic nerves and at neuromuscular junctions
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Bioavailibility
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Subcategory of absorption; the percentage of the admin drug dose that reaches the systemic circulation
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Chronotropic
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Process that influences the heart rate (can be positive or negative)
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Cross- tolerance
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Tolerance for a medication one has not taken before as a result of using another medication in the same drug class
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Cumulative effect
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The increasing response to repeated doses of a drug that occurs when the rate of administration exceeds the rate of metabolism or excretion
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Depolarizing agents
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Medications that cause neuromuscular blockake by binding and briefly activating receptor sites at the neuromuscular junction, preventing further activation of thses sites and causing chemical paraylsis
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Dromotropic
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Process that influences the conduction velocity of nerve or muscle fibers (can be positive or negative)
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Drug antagonism
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The interaction between two drugs where one partially or completely inhibits the effects of the other
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Drug interaction
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Alteration in the pharmacologic activity of a given drug caused by the presence of one or more additional drugs
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Duration of action
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The length of time the concentration of a drug in the blood or tissues is sufficient to elicit a pharmacological response
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First- order elimination
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Characterized by the a medication's rate of elimination being dependent on it's concentration in plasma
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First- pass effect
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The initial metabolism in the liver of a drug absorbed from the gastrointestinal tract before the drug reaches systemic circulation through the bloodstream
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Half- life
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The time required to eliminate half of the amount of the medication from the plasma
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Iatrogenic response
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An adverse condition inadvertently induced in a patient by the treatment given.
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Idiosyncrasy
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An abnormal reaction to a medication that most persons DO NOT experience
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