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Transketolase is an enzyme that catalyzes:
a. transfer of three-carbon units from a ketose to an aldose b. transfer of ketoses into aldoses c. transfer of xylulose-5-phosphate into ribulose-5-phosphate d. TPP-dependent transfer of 2-carbon units to the recipient aldose e. transfer of keto groups from C-2 to C-3 |
D. TPP-dependent transfer of 2-carbon units to the recipient aldose
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Which of the following reactions is catalyzed by a transketolase in the
pentose phosphate pathway?
I.
fructose-6-P + glyceraldehyde-3-P à xylulose-5-P +
erythrose-4-P
II.
erythrose-4-P + fructose-6-P à sedoheptulose-7-P + glyceraldehyde-3-P
III.
sedoheptulose-7-P + glyceraldehyde-3-P à ribose-5-P + xylulose-5-P
a. I only
b. II and III
c. II only
d. I and III
e. I and II
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D. I and III
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The transaldolase catalyzed activity is similar to what glycolytic
enzyme?
a. phosphoglucomutase
b. enolase
c. glyceraldehyde-3-phosphate dehydrogenase
d. PFK-1
e. aldolase
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E. aldolase
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When a cell with the pentose phosphate pathway has need for more
pentose phosphates, but no additional NADPH:
a. glucose-6-phosphate dehydrogenase is activated b. the oxidative and no=oxidate enzymes of the petose phosphate pathway are active c. the non-oxidative enzymes produce pentose phosphates form fructose-6-phosphate and glyceraldehyde-3-phosphate d. all enzymes of glycolysis and pentose phosphate pathway are active e. none |
C. the non-oxidative enzymes produce pentose phosphates form fructose-6-phosphate and glyceraldehyde-3-phosphate
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The primary stoarage form of lipid is ___ and it is normally stored in
the ____.
a. phospholipid; liver
b. cholesterol; muscles
c. monoacylglycerol; adipocytes
d. triacylglycerols; adipocytes
e. tracylglycerols; liver
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D. triacylglycerols; adipocytes
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The sequence for activation of the release of fatty acids from adipose
cells:
A. protein kinase activation
B.
camp production
C.
triacylgylcerol lipase activationD.
hormone binding receptor
E.
adenylyl cyclase activation
F.
diacyglycerol lipase and monoacylglycerol lipase activity
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D,E,B,A,C,F
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Fatty acids are mobilized from adipose cells in response to all of the
hormones EXCEPT:
a. ACTH
b. glucagon
c. insulin
d. epinephrine
e. all
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C. insulin
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Bile salts are important in the initial digestion of triacylgylcerols
in the intestine because they:
a. are coenzymes for pancreatic lipases
b. convert the inactive lipase into the active form
c. emulsify the triacylglycerol globules to produce greater surface
area which will increase the activity of the lipase
d. activate the cleavage at the C-2 position
e. permit greater permeability of the triacylglycerols through the
intestinal memrane
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C. emulsify the triacylglycerol globules to produce greater surface area which will increase the activity of the lipase
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The majority of lipid digestion occurs in the duodenum by the enzyme
_____ that produces ____ and _____ for absorption.
a. acid lipase; diacylglycerols; fatty acids
b. triacylglycerol lipase; fatty acids; glycerol
c. triacylglycerol lipase; fatty acids; glycerol
d. pancreatic lipase; monoacylgylcerols; fatty acids
e. pancreatic lipase; glycerol; fatty acids
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D. pancreatic lipase; monoacylgylcerols; fatty acids
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Absorbed lipids are condensed with glycerol in the epithelial cells
into ____ and re-packaged into _____ that are initially transported by the ____
system.
a. phospholipids; VLDL; lymphatic
b. triacylglycerols; VLDL; portal
c. triacylglycerols; chylomicron; portal
d. triacylglycerols; chylomicron; lymphatic
e. triacylglycerols; VLDL; lymphatic
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D. triacylglycerols; chylomicron; lymphatic
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Chylomicrons:
a. a formed in adipose tissue
b. are primary energy sources for the brain
c. transport dietary triacylglycerols through the bloodstream
d. are formed in and secreted by the liver
e. contain more phospholipid than triacylglycerol molecules
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C. transport dietary triacylglycerols through the bloodstream
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Where in the cell are fatty acids condensed with coenzyme A to form
acyl-CoA for beta-oxidation?
a. mitochondrial matrix
b. cytoplasm
c. outer mitochondrial membrane
d. inner mitochondrial membrane
e. none
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C. outer mitochondrial membrane
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__ carries long chain fatty acyl groups across the ____ membrane.
a. biotin; intestinal
b. carnitinel plasma
c. CoA-SH; plasma
d. carnitine; inner mitochondrial
e. TPP; outer mitochondrial
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D. carnitine; inner mitochondrial
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The correct sequence for transport of fatty acyl groups from the
cytosol to the matrix is”
A.
carnitine acytransferase I
B.
translocase of carnitine and O-acyl carnitine
C.
carnitine acyltransferase II
D.
fatty acyl-CoA synthesis
E.
O-acylcarnitine F. oops
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D,A,E,B,C,F
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The first 3 rxns of beta-oxidation of saturated FAs are analogous to
which sequence of metabolic rxns already discussed?
a. succinateàfumarateàmalateàoxaoloacetate
b. isocitrateàalpha-ketoglutarateàsuccinateàfumarate
c. OAAàcitrateàisocitrateàalpha-keto
d. phosphoenolpyruvateàPiàacetyl-Coaàcitrate
e. alpha-ketoà succinyl coAàsuccinateàfumarate
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A. succinateàfumarateàmalateàoxaoloacetate
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