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Acetylcholine (ACh) in central nervous system
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REM sleep, regulation of sleep-wake cycle, memory (Alzheimers)
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Acetylcholine (ACh) in peripheral nervous system
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Causes muscles to contract
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Acetylcholine: 2 types of cholinergic receptors
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Nicotine (excitatory), muscarinic (inhibitory)
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Names of neurotransmitters included in the Catecholamines
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Norepinephrine, epinephrine, dopamine
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Functions of catecholamines
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Personality, mood, memory, sleep
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Low levels of norepinephrine and dopamine
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Some forms of depression
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Excessive activity at dopamine synapses
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Schizophrenia and Tourette's
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A dopamine function
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Regulation of movement
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Degeneration of dopamine receptors in substantia nigra
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Parkinson's symptoms (tremors, muscle rigidity, other motor symptoms)
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Elevated levels of dopamine in mesolimbic system
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Reinforcing actions of stimulant drugs, opiates, alcohol, and nicotine
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Serotonin (5-HT)
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Inhibitory; mood, hunger, temperature regulation, sexual activity, arousal, sleep, aggression, and migraine headache
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Elevated levels of serotonin
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Schizophrenia and autism
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Low levels of serotonin
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Depression, suicide, PTSD, OCD, aggression
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Gamma-aminobutyric acid (GABA)
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Inhibitory; sleep, eating, seizure, anxiety
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Degeneration of cells that secrete GABA in basal ganglia
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Motor symptoms of Huntington's
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