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Hormone
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A chemical substance produced in the body
that controls and regulates the activity of certain cells or organs.
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Target Cell - Target Organ
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An endocrine organ/cell of which the functional activity is controlled by hormones.
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Negative Feedback
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Feedback that tends to stabilize a process by reducing its rate or output when its effects are too great.
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Difference between edocrine and exocrine glands.
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Endocrine glands are ductless and produce internal secretion. Exocrine glands have ducts that release secretions to the external surfaces of the body.
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Steroid Hormone Action (direct gene activation) &
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1. diffuse 2. enter nucleus 3. binds to receptor 4. binds to DNA sites 5. activating genes 6. translated in cytoplasm resulting in synthesis
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Endocrine Gland Stimulation -hormonal-humoral-neural
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-triggered by some internal or external stimulus. --most common, endocrine organs are prodded into action by other hormones (calcitonin/insulin) --changes blood levels of ions or nutrients --nerve stimulating fibers (nor/epinephrine)
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Hyperthyroidism
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Excessive functional activity of the thyroid gland.
Increased metabolic rate, enlargement of the thyroid gland, rapid heart rate, and high blood pressure |
Grave's Disease
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One form of hyperthyroidism.
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Exophthalmos
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Abnormal protrusion of the eyeball.
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Goiter
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Enlargement of the thyroid gland.
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Myxedema
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Severe hypothyroidism characterized by firm inelastic edema, dry skin and hair, and loss of mental and physical vigor.
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Hyperparathyroidism
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Excess parathyroid hormone in the body resulting in disturbance of
calcium metabolism with loss of calcium from bone. Destroys the bony matrix.
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Calcitonin & Parathyroid Hormone (PTH)
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Calcitonin lowers the level of calcium in the blood plasma. PTH regulates the metabolism of calcium in the body.
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Cortisol
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A Glucocorticoid that: 1. convert proteins & fats to glucose 2. increase blood sugar 3. suppress immune system
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Aldosterone
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A Mineralocorticoid that: 1. retention of sodium and water by kidneys 2. increase blood volume and blood pressure.
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