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Cards In This Set
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Axon guidance
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Moving axons to the places where they need to be in order to make synapses
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Brainbow Mouse
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Use Cre-Lox to get 90 different colored neurons in mouse brain
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What are the 3 components of the car trip analogy? Axon needs:
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1. Motor ability
2. Senory ability to respond to environment 3. Adaptation (respond differently to same molecules, which is done via different receptors) |
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Who first discovered the growth cone, and what was his theory of its function?
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1. Ramon y Cajal
2. Believed it was a battering ram to get developing axons through matter |
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_________ and _________ of growth cone are dependent on the needs of an axon because of a changing __________.
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Morphology; Speed; Environment
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Leader axons
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First axons, have more complex growth cones
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Follower axons
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Simpler growth cones
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Two advantages to using Aplysia to study growth cones
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1. Huge axons
2. Huge growth cones |
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Actin's place on GC
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Edge of cone
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Filopodia
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Finger-like extension made from actin bundles
The way that the growth cone moves |
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Lamelipodia
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Sheet membrane between filopodia, made of actin filaments
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Growth cone _________ & ________ ______ through time
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Elongates; changes shape
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Axons elongate from the ________ end. How?
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Growing; Addition of microtubules @ GCs
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Where is actin on the growth cone?
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The edge
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What do microtubules do for the growth cone
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Provide structure
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