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Cards In This Set
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IL1
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Secredetd by macro's. Causes acute inflammation. Induces chmokine production to recruit leukocytes; activates endothelium to express adhesion molecules. An endogenous pyrogen.
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IL-2
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Secreted by Th cells. Stimulates growth of helper and cytototoxic T cells.
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IL-3
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Secreted by activated T cells. Supports teh growth and differentiation of bone bmarrrow stem cells. Has a similar function to GM-CSF.
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Il-4
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Secreted by Th2 cells. Promotes differentiation of B cell.s Enhances class switching to IgA. Stimulates production and activation of eosinophils.
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Il-6
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Secreted by Th cells and macrophages. Stimulates production of acute-phase reactants and immunoglobulins.
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IL-5
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Secreted by Th2 cells Promotes differentiation of Bcells. Enhances class switching to IgA. Stimulates production and activation of eosinophils.
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IL-8
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Secreted by macrophages. Major chemtactic factor for neutrophils.
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Secreted by macrophages.
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Major chemotactic factor for neutrophils
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Il-10
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Secreted by regulatory T cells. Inhibits actions of activated T cells.
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Il-12
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Secreted by B cells and macrophages. Activates NK and Th1 cells.
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Y-interferon
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Secreted by Th1 cells. Stimulates macrophages.
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TNF
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Secreted by macrophages. Mediates septic shock. Causes leukocyte recruitment, vascular rleak. cachexia-supppresses appetite, inhibits lipoporotein lipase and increases insulin resistance of peripheral tissues.
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IFN-alpha
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The IFN-α proteins are produced by leukocytes. They are mainly involved in innate immune response against viral infection. They
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