The Heart Lecture 8

72 cards   |   Total Attempts: 188
  

Cards In This Set

Front Back
In a cardiac muscle contraction _________ of the heart is rhythmic and spontaneous
Depolarization
What do gap junctions do?
Ensure the heart contracts as a unit
In cardiac muscle contraction depolarization opens what?
Voltage gated Na+ channels in the sarcolemma
Reversal of membrane potential goes from what to what?
-90mv to +30 mv
Depolarization wave in T tubules causes the SR to what?
Release Ca2+
In cardiac muscle contraction depolarization wave does what?
Opens slow Ca2 channels in the sarcolemma
In cardiac muscle contraction Ca2+ surge does what?
Prolongs depolarization phase (plateau)
Depolarization is due to what?
Na+ influx through fast voltage gated Na+ channels.
In depolarization a positive feedback cycle rapidly opens many Na+ channels doing what?
Reversing the membrane potential. channel inactivation ends this phase
The plateau phase is due to what?
Ca2+ influx through slow Ca2+
In the plateau phase the Ca2+ influx through slow Ca2+ channels does what?
Keeps the cell depolarized because few K+ channels are open for overflow
Repolarization is due to what?
Inactivation of Ca2+ channels and opening of K+ channels.
In repolarization Inactivation of Ca+ channels and opening of K+ channels allows what?
Allows K+ efflux, which brings the membrane potential back to its resting voltage
Ca2 influx triggers what?
Opening of Ca2+ sensitive channels in the SR, which opens up bursts of Ca2+
Excitation- contracting coupling occurs as Ca2+ binds to tropinin which allows what?
Actin and myosin filaments to begin sliding past one another